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Acentrosomal Drosophila epithelial cells exhibit abnormal cell division, leading to cell death and compensatory proliferation

Mitotic spindles are critical for accurate chromosome segregation. Centrosomes, the primary microtubule nucleating centers of animal cells, play key roles in forming and orienting mitotic spindles. However, the survival of Drosophila without centrosomes suggested they are dispensable in somatic cell...

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Bibliographische Detailangaben
Hauptverfasser: Poulton, John S, Cuningham, John C, Peifer, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182331/
https://ncbi.nlm.nih.gov/pubmed/25241934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.08.007
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