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Genomic and Proteomic Pathophysiology of Pseudoexfoliation Glaucoma

PEX stems from a pathologic elastotic process involving the cross-linking gene lysyl oxidase-like-1 (LOXL1), and is associated with abnormal formation of elastic extracellular matrix. We previously described a protein sink model to explain PEX material deposition on the lens capsule and other intrao...

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Detalhes bibliográficos
Main Authors: Vazquez, Luis E., Lee, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182319/
https://ncbi.nlm.nih.gov/pubmed/25171640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IIO.0000000000000047
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