Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen.

Because of variations in tRNA sequences in evolution, tRNA synthetases either do not acylate their cognate tRNAs from other organisms or execute misacylations which can be deleterious in vivo. We report here the cloning and primary sequence of a 958-aa Saccharomyces cerevisiae alanyl-tRNA synthetase...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Ripmaster, T L, Shiba, K, Schimmel, P
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1995
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.4932
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