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Fusion of CTLA-4 with HPV16 E7 and E6 Enhanced the Potency of Therapeutic HPV DNA Vaccine

Preventive anti-HPV vaccines are effective against HPV infection but not against existing HPV-associated diseases, including cervical cancer and other malignant diseases. Therefore, the development of therapeutic vaccines is urgently needed. To improve anti-tumor effects of therapeutic vaccine, we f...

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Autors principals: Gan, Lili, Jia, Rong, Zhou, Lili, Guo, Jihua, Fan, Mingwen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181872/
https://ncbi.nlm.nih.gov/pubmed/25265018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108892
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