Silk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats

PURPOSE: We aimed to evaluate the intestinal anti-inflammatory properties of silk fibroin nanoparticles, around 100 nm in size, when loaded with the stilbene compound resveratrol, in an experimental model of rat colitis. METHODS: Nanoparticles were loaded with resveratrol by adsorption. The biologic...

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Bibliographische Detailangaben
Hauptverfasser: Lozano-Pérez, Antonio Abel, Rodriguez-Nogales, Alba, Ortiz-Cullera, Víctor, Algieri, Francesca, Garrido-Mesa, José, Zorrilla, Pedro, Rodriguez-Cabezas, M Elena, Garrido-Mesa, Natividad, Utrilla, M Pilar, De Matteis, Laura, de la Fuente, Jesús Martínez, Cenis, José Luis, Gálvez, Julio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181735/
https://ncbi.nlm.nih.gov/pubmed/25285004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S68526
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