X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination

[Image: see text] Crystallization from lipidic mesophase matrices is a promising route to diffraction-quality crystals and structures of membrane proteins. The microfluidic approach reported here eliminates two bottlenecks of the standard mesophase-based crystallization protocols: (i) manual prepara...

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Main Authors: Khvostichenko, Daria S., Schieferstein, Jeremy M., Pawate, Ashtamurthy S., Laible, Philip D., Kenis, Paul J. A.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181584/
https://ncbi.nlm.nih.gov/pubmed/25285049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cg5011488
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