Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment

Tumor-associated macrophages play an important role in tumor growth and progression. These macrophages are heterogeneous with diverse functions, eg, M1 macrophages inhibit tumor growth, whereas M2 macrophages promote tumor growth. In this study, we found that IFNγ and/or celecoxib (cyclooxygenase-2...

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Detalhes bibliográficos
Main Authors: Ren, Fuqiang, Fan, Mingyu, Mei, Jiandong, Wu, Yongqiang, Liu, Chengwu, Pu, Qiang, You, Zongbing, Liu, Lunxu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181549/
https://ncbi.nlm.nih.gov/pubmed/25284985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S66302
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