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Long-term efficacy and safety of once-daily mesalazine granules for the treatment of active ulcerative colitis
In 1977, 5-aminosalicylic acid (5-ASA) was discovered as a therapeutically active moiety of sulfasalazine (SASP) and was launched for topical and oral therapy of ulcerative colitis (UC) in 1984. As a first-step, delivery systems had to be developed to protect 5-ASA against absorption in the upper ga...
Gespeichert in:
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4181447/ https://ncbi.nlm.nih.gov/pubmed/25285021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S35691 |
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