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Long-term efficacy and safety of once-daily mesalazine granules for the treatment of active ulcerative colitis

In 1977, 5-aminosalicylic acid (5-ASA) was discovered as a therapeutically active moiety of sulfasalazine (SASP) and was launched for topical and oral therapy of ulcerative colitis (UC) in 1984. As a first-step, delivery systems had to be developed to protect 5-ASA against absorption in the upper ga...

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Hlavní autoři: Böhm, Stephan Karl, Kruis, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181447/
https://ncbi.nlm.nih.gov/pubmed/25285021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S35691
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