Longitudinal Analysis of DNA Methylation in CD34+ Hematopoietic Progenitors in Myelodysplastic Syndrome

Myelodysplastic syndrome (MDS) is a disorder of hematopoietic stem cells (HSCs) that is often treated with DNA methyltransferase 1 (DNMT1) inhibitors (5-azacytidine [AZA], 5-aza-2′-deoxycytidine), suggesting a role for DNA methylation in disease progression. How DNMT inhibition retards disease progr...

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Hlavní autoři: Wong, Yan-Fung, Micklem, Chris N., Taguchi, Masataka, Itonaga, Hidehiro, Sawayama, Yasushi, Imanishi, Daisuke, Nishikawa, Shinichi, Miyazaki, Yasushi, Jakt, Lars Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2014
Témata:
Cancer Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181398/
https://ncbi.nlm.nih.gov/pubmed/25122688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0035
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