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Tyrosine kinase inhibition: A therapeutic target for the management of chronic-phase chronic myeloid leukemia
Chronic myeloid leukemia (CML) is a hematologic neoplasm with a progressive, ultimately terminal, disease course. In most cases, CML arises owing to the aberrant formation of a chimeric gene for a constitutively active tyrosine kinase. Inhibition of the signaling activity of this kinase has proved t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4181370/ https://ncbi.nlm.nih.gov/pubmed/24236822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2013.859074 |
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