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An Overview of the Effects of anti-IgE Therapies
Omalizumab, a humanized mAb that binds to the CH3 domain near the binding site for the high-affinity type-I IgE Fc receptors of human IgE, can neutralize free IgE and inhibit the IgE allergic pathway without sensitizing mast cells and basophils. We found that omalizumab in patients with severe persi...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Scientific Literature, Inc.
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4181307/ https://ncbi.nlm.nih.gov/pubmed/25241913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.890137 |
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