The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia

The transcription factor Sox4 plays an indispensable role in the development of early progenitor B cells from hematopoietic stem cells. However, its role in B-cell acute lymphoblastic leukemia, a malignant counterpart of normal progenitor B cells, is not fully understood. Here we show that SOX4 is h...

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Auteurs principaux: Ma, Haiqing, Mallampati, Saradhi, Lu, Yue, Sun, Baohua, Wang, Enze, Leng, Xiaohong, Gong, Yun, Shen, Haifa, Yin, C. Cameron, Jones, Dan, Amin, Hesham M., You, M. James, Zweidler-McKay, Patrick, Ma, Yupo, Kantarjian, Hagop M., Arlinghaus, Ralph B., Glassman, Armand, Sun, Xiaoping
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181255/
https://ncbi.nlm.nih.gov/pubmed/24997151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.104695
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