Maternal Methylenetetrahydrofolate Reductase C677T Polymorphism and Down Syndrome Risk: A Meta-Analysis from 34 Studies

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of folate metabolic pathway which catalyzes the irreversible conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. 5-methyltetrahydrofolate donates methyl group for the methylation of homocysteine to methion...

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Bibliografske podrobnosti
Main Authors: Rai, Vandana, Yadav, Upendra, Kumar, Pradeep, Yadav, Sushil Kumar, Mishra, Om Prakesh
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180743/
https://ncbi.nlm.nih.gov/pubmed/25265565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108552
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