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Implication of the cause of differences in 3D structures of proteins with high sequence identity based on analyses of amino acid sequences and 3D structures

BACKGROUND: Proteins that share a high sequence homology while exhibiting drastically different 3D structures are investigated in this study. Recently, artificial proteins related to the sequences of the GA and IgG binding GB domains of human serum albumin have been designed. These artificial protei...

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主要な著者: Matsuoka, Masanari, Sugita, Masatake, Kikuchi, Takeshi
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180342/
https://ncbi.nlm.nih.gov/pubmed/25231773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-654
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