Role of tumor molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

OBJECTIVE: To estimate risk of colorectal cancer (CRC) for first-degree relatives of CRC cases based on CRC molecular subtypes and tumor pathology features. DESIGN: We studied a cohort of 33,496 first-degree relatives of 4,853 incident invasive CRC cases (probands) who were recruited to the Colon Ca...

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Autors principals: Win, Aung Ko, Buchanan, aniel D., Rosty, Christophe, MacInnis, Robert J., Dowty, James G., Dite, Gillian S., Giles, Graham G., Southey, Melissa C., Young, Joanne P., Clendenning, Mark, Walsh, Michael D., Walters, Rhiannon J., Boussioutas, Alex, Smyrk, Thomas C., Thibodeau, Stephen N., Baron, John A., Potter, John D., Newcomb, Polly A., Marchand, Loïc Le, Haile, Robert W., Gallinger, Steven, Lindor, Noralane M., Hopper, John L., Ahnen, Dennis J., Jenkins, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180004/
https://ncbi.nlm.nih.gov/pubmed/24615377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306567
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