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Increasing Doxycycline Hyclate Photostability by Complexation with β-Cyclodextrin

Doxycycline hyclate (DOX) is a highly photosensitive drug, a feature that limits the stability of the corresponding dosage forms. The main objectives of this work were the preparation and characterization of an inclusion complex of DOX with β-cyclodextrin (βCD) and to investigate if this approach co...

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Detalhes bibliográficos
Main Authors: Kogawa, Ana Carolina, Zoppi, Ariana, Quevedo, Mario Alfredo, Nunes Salgado, Hérida Regina, Longhi, Marcela Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179669/
https://ncbi.nlm.nih.gov/pubmed/24889734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0150-7
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