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Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer

Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community. Since the 1880s, laboratory diagnosis of tuberculosis has relied primarily on mic...

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Main Authors: Doughty, Emma L., Sergeant, Martin J., Adetifa, Ifedayo, Antonio, Martin, Pallen, Mark J.
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179564/
https://ncbi.nlm.nih.gov/pubmed/25279265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.585
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