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Production of recombinant human proinsulin in the milk of transgenic mice

There is a steady increasing demand for insulin worldwide. Current insulin manufacturing capacities can barely meet this increasing demand. The purpose of this study was to test the feasibility of producing human proinsulin in the milk of transgenic animals. Four lines of transgenic mice harboring a...

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Autori principali: Qian, Xi, Kraft, Jana, Ni, Yingdong, Zhao, Feng-Qi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179469/
https://ncbi.nlm.nih.gov/pubmed/25267062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06465
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