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Rapid, Scalable Assembly of Stereochemically Rich, Mono- and Bicyclic Acyl Sultams

[Image: see text] A one-pot, sequential protocol is reported that involves complementary ambiphile pairing (CAP) of a vinyl sulfonamide with a variety of unprotected amino acids via aza-Michael addition and subsequent intramolecular amidation. The method generates diverse, sp(3)-rich mono- and bicyc...

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Bibliografiske detaljer
Main Authors: Asad, Naeem, Samarakoon, Thiwanka B., Zang, Qin, Loh, Joanna K., Javed, Salim, Hanson, Paul. R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179432/
https://ncbi.nlm.nih.gov/pubmed/24313225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol403070w
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