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The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation

The control of chromosome segregation relies on the spindle assembly checkpoint (SAC), a complex regulatory system that ensures the high fidelity of chromosome segregation in higher organisms by delaying the onset of anaphase until each chromosome is properly bi-oriented on the mitotic spindle. Cent...

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Autors principals: Lee, Semin, Bolanos-Garcia, Victor M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179342/
https://ncbi.nlm.nih.gov/pubmed/25324779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00368
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