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Altered Gene Expression in Blood and Sputum in COPD Frequent Exacerbators in the ECLIPSE Cohort

Patients with chronic obstructive pulmonary disease (COPD) who are defined as frequent exacerbators suffer with 2 or more exacerbations every year. The molecular mechanisms responsible for this phenotype are poorly understood. We investigated gene expression profile patterns associated with frequent...

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Autores principales: Singh, Dave, Fox, Steven M., Tal-Singer, Ruth, Bates, Stewart, Riley, John H., Celli, Bartolome
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179270/
https://ncbi.nlm.nih.gov/pubmed/25265030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107381
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