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Toxin ζ Reversible Induces Dormancy and Reduces the UDP-N-Acetylglucosamine Pool as One of the Protective Responses to Cope with Stress

Toxins of the ζ/PezT family, found in the genome of major human pathogens, phosphorylate the peptidoglycan precursor uridine diphosphate-N-acetylglucosamine (UNAG) leading to unreactive UNAG-3P. Transient over-expression of a PezT variant impairs cell wall biosynthesis and triggers autolysis in Esch...

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Detalhes bibliográficos
Main Authors: Tabone, Mariangela, Ayora, Silvia, Alonso, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179160/
https://ncbi.nlm.nih.gov/pubmed/25238046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6092787
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