Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Steroidogenic acute regulatory protein (StAR) appears to mediate the rapid increase in pregnenolone synthesis stimulated by tropic hormones. cDNAs encoding StAR were isolated from a human adrenal cortex library. Human StAR, coexpressed in COS-1 cells with cytochrome P450scc and adrenodoxin, increase...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sugawara, T, Holt, J A, Driscoll, D, Strauss, J F, Lin, D, Miller, W L, Patterson, D, Clancy, K P, Hart, I M, Clark, B J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761400/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.4778
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