Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity

Rat and mouse adrenal medullary chromaffin cells (CCs) express an inactivating BK current. This inactivation is thought to arise from the assembly of up to four β2 auxiliary subunits (encoded by the kcnmb2 gene) with a tetramer of pore-forming Slo1 α subunits. Although the physiological consequences...

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Hauptverfasser: Martinez-Espinosa, Pedro L., Yang, Chengtao, Gonzalez-Perez, Vivian, Xia, Xiao-Ming, Lingle, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178941/
https://ncbi.nlm.nih.gov/pubmed/25267913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411253
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