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Pegylated Interferon Pharmacokinetics and Self-Reported Depressive Symptoms During Antiviral Treatment for Chronic Hepatitis C

BACKGROUND: Pegylated interferon-2a (PegIFN-2a) + ribavirin treatment for chronic hepatitis C is often associated with depressive symptoms. Previous studies have failed to explore whether PegIFN-2a pharmacokinetic variability plays an etiologic role in PegIFN-2a-induced mood disorders. The objective...

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Bibliographic Details
Main Authors: Evon, Donna M., Esserman, Denise E., Howell, Meredith A., Ruffin, Rachel A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178927/
https://ncbi.nlm.nih.gov/pubmed/25121993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0034-1385929
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