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Contribution of Glutamine Residues in the Helix 4-5 Loop to Capsid-Capsid Interactions in Simian Immunodeficiency Virus of Macaques

Following retrovirus entry, the viral capsid (CA) disassembles into its component capsid proteins. The rate of this uncoating process, which is regulated by CA-CA interactions and by the association of the capsid with host cell factors like cyclophilin A (CypA), can influence the efficiency of rever...

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Autori principali: Tipper, Christopher, Sodroski, Joseph G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178892/
https://ncbi.nlm.nih.gov/pubmed/24991000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01388-14
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