Prophylaxis with a Respiratory Syncytial Virus (RSV) Anti-G Protein Monoclonal Antibody Shifts the Adaptive Immune Response to RSV rA2-line19F Infection from Th2 to Th1 in BALB/c Mice

Respiratory syncytial virus (RSV) is the single most important cause of serious lower respiratory tract infections in young children, yet no highly effective treatment or vaccine is available. In the present study, we investigated the effect of prophylactic treatment with the intact and F(ab′)(2) fo...

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Hlavní autoři: Boyoglu-Barnum, Seyhan, Chirkova, Tatiana, Todd, Sean O., Barnum, Thomas R., Gaston, Kelsey A., Jorquera, Patricia, Haynes, Lia M., Tripp, Ralph A., Moore, Martin L., Anderson, Larry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178873/
https://ncbi.nlm.nih.gov/pubmed/24990999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01503-14
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