Toll-Like Receptor 9-Mediated Protection of Enterovirus 71 Infection in Mice Is Due to the Release of Danger-Associated Molecular Patterns

Enterovirus 71 (EV71), a positive-stranded RNA virus, is the major cause of hand, foot, and mouth disease (HFMD) with severe neurological symptoms. Antiviral type I interferon (alpha/beta interferon [IFN-α/β]) responses initiated from innate receptor signaling are inhibited by EV71-encoded proteases...

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Autors principals: Hsiao, Hung-Bo, Chou, Ai-Hsiang, Lin, Su-I, Chen, I-Hua, Lien, Shu-Pei, Liu, Chia-Chyi, Chong, Pele, Liu, Shih-Jen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178751/
https://ncbi.nlm.nih.gov/pubmed/25078697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00867-14
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