Aod1, the immunoregulatory locus controlling abrogation of tolerance in neonatal thymectomy-induced autoimmune ovarian dysgenesis, maps to mouse chromosome 16.

Mice thymectomized at three days of age (D3Tx) develop during adulthood a variety of organ-specific autoimmune diseases, including autoimmune ovarian dysgenesis (AOD). The phenotypic spectrum of AOD is characterized by the development of anti-ovarian autoantibodies, oophoritis, and atrophy. The D3Tx...

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Bibliografiske detaljer
Main Authors: Wardell, B B, Michael, S D, Tung, K S, Todd, J A, Blankenhorn, E P, McEntee, K, Sudweeks, J D, Hansen, W K, Meeker, N D, Griffith, J S
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41786/
https://ncbi.nlm.nih.gov/pubmed/7761397
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