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Vitamin B(6) Generated by Obligate Symbionts Is Critical for Maintaining Proline Homeostasis and Fecundity in Tsetse Flies

The viviparous tsetse fly utilizes proline as a hemolymph-borne energy source. In tsetse, biosynthesis of proline from alanine involves the enzyme alanine-glyoxylate aminotransferase (AGAT), which requires pyridoxal phosphate (vitamin B(6)) as a cofactor. This vitamin can be synthesized by tsetse�...

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Detalhes bibliográficos
Main Authors: Michalkova, Veronika, Benoit, Joshua B., Weiss, Brian L., Attardo, Geoffrey M., Aksoy, Serap
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178588/
https://ncbi.nlm.nih.gov/pubmed/25038091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01150-14
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