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Approaches to integrating germline and tumor genomic data in cancer research
Cancer is characterized by a diversity of genetic and epigenetic alterations occurring in both the germline and somatic (tumor) genomes. Hundreds of germline variants associated with cancer risk have been identified, and large amounts of data identifying mutations in the tumor genome that participat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4178473/ https://ncbi.nlm.nih.gov/pubmed/25115441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu165 |
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