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Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism

The increased glucose metabolism in cancer cells is required to fulfill their high energetic and biosynthetic demands. Changes in the metabolic activity of cancer cells are caused by the activation of oncogenes or loss of tumor suppressors. They can also be part of the metabolic adaptations to the c...

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Bibliographic Details
Main Authors: Ros, Susana, Schulze, Almut
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178209/
https://ncbi.nlm.nih.gov/pubmed/24280138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-8
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