Flavonoid Fraction of Bergamot Juice Reduces LPS-Induced Inflammatory Response through SIRT1-Mediated NF-κB Inhibition in THP-1 Monocytes

Plant polyphenols exert anti-inflammatory activity through both anti-oxidant effects and modulation of pivotal pro-inflammatory genes. Recently, Citrus bergamia has been studied as a natural source of bioactive molecules with antioxidant activity, but few studies have focused on molecular mechanisms...

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Bibliographic Details
Main Authors: Risitano, Roberto, Currò, Monica, Cirmi, Santa, Ferlazzo, Nadia, Campiglia, Pietro, Caccamo, Daniela, Ientile, Riccardo, Navarra, Michele
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178028/
https://ncbi.nlm.nih.gov/pubmed/25260046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107431
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