CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression

Expression of co-inhibitory molecules is generally associated with T-cell dysfunction in chronic viral infections such as HIV or HCV. However, their relative contribution in the T-cell impairment remains unclear. In the present study, we have evaluated the impact of the expression of co-inhibitory m...

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Autors principals: Viganò, Selena, Banga, Riddhima, Bellanger, Florence, Pellaton, Céline, Farina, Alex, Comte, Denis, Harari, Alexandre, Perreau, Matthieu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177992/
https://ncbi.nlm.nih.gov/pubmed/25255144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004380
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