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Atomistic Insights into Human Cys-loop Receptors by Solution NMR

Cys-loop receptors are pentameric ligand-gated ion channels (pLGICs) mediating fast neurotransmission in the central and peripheral nervous systems. They are important targets for many currently used clinical drugs, such as general anesthetics, and for allosteric modulators with potential therapeuti...

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Detalhes bibliográficos
Main Authors: Mowrey, David D., Kinde, Monica N., Xu, Yan, Tang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177975/
https://ncbi.nlm.nih.gov/pubmed/24680782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.03.014
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