Clinical Validation and Implications of Dried Blood Spot Sampling of Carbamazepine, Valproic Acid and Phenytoin in Patients with Epilepsy

To facilitate therapeutic monitoring of antiepileptic drugs (AEDs) by healthcare professionals for patients with epilepsy (PWE), we applied a GC-MS assay to measure three AEDs: carbamazepine (CBZ), phenytoin (PHT) and valproic acid (VPA) levels concurrently in one dried blood spot (DBS), and validat...

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Detalhes bibliográficos
Main Authors: Kong, Sing Teang, Lim, Shih-Hui, Lee, Wee Beng, Kumar, Pasikanthi Kishore, Wang, Hwee Yi Stella, Ng, Yan Lam Shannon, Wong, Pei Shieen, Ho, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177879/
https://ncbi.nlm.nih.gov/pubmed/25255292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108190
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