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κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation

Transformation of cells generally involves multiple genetic lesions that undermine control of both cell death and proliferation. We now report that κB-Ras proteins act as regulators of NF-κB and Ral pathways, which control inflammation/cell death and proliferation, respectively. Cells lacking κB-Ras...

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Main Authors: Oeckinghaus, Andrea, Postler, Thomas S., Rao, Ping, Schmitt, Heike, Schmitt, Verena, Grinberg-Bleyer, Yenkel, Kühn, Lars I., Gruber, Christian W., Lienhard, Gustav E., Ghosh, Sankar
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177457/
https://ncbi.nlm.nih.gov/pubmed/25220458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.015
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