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Cisplatin exposure damages resident stem cells of the mammalian inner ear

BACKGROUND: Cisplatin is a widely-used chemotherapeutic agent that can also cause ototoxic injury. One potential treatment for cisplatin-induced hearing loss involves the activation of endogenous inner ear stem cells, which may then produce replacement hair cells. In this series of experiments, we e...

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Detalhes bibliográficos
Main Authors: Slattery, Eric L., Oshima, Kazuo, Heller, Stefan, Warchol, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177445/
https://ncbi.nlm.nih.gov/pubmed/24888499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24150
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