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The Role of Heparan Sulfate Proteoglycans in Optic Disc and Stalk Morphogenesis

BACKGROUND: Heparan sulfate proteoglycans (HSPG) are important for embryonic development via the regulation of gradient formation and signaling of multiple growth factors and morphogens. Previous studies have shown that Bmp/Shh/Fgf signaling are required for the regionalization of the optic vesicle...

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Detalles Bibliográficos
Main Authors: Cai, Zhigang, Grobe, Kay, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177358/
https://ncbi.nlm.nih.gov/pubmed/24753163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24142
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