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Increased G Protein-Coupled Receptor Kinase (GRK) Expression in the Anterior Cingulate Cortex in Schizophrenia

BACKGROUND: Current pharmacological treatments for schizophrenia target G protein-coupled receptors (GPCRs), including dopamine receptors. Ligand bound GPCRs are regulated by a family of G protein-coupled receptor kinases (GRKs), members of which uncouple the receptor from heterotrimeric G proteins,...

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Detalhes bibliográficos
Main Authors: Funk, Adam J., Haroutunian, Vahram, Meador-Woodruff, James H., McCullumsmith, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177355/
https://ncbi.nlm.nih.gov/pubmed/25153362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.07.040
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