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Structure-Based Simulations Reveal Concerted Dynamics of GPCR Activation
G protein-coupled receptors (GPCRs) are a vital class of proteins that transduce biological signals across the cell membrane. However, their allosteric activation mechanism is not fully understood; crystal structures of active and inactive receptors have been reported, but the functional pathway bet...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177312/ https://ncbi.nlm.nih.gov/pubmed/24889093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24617 |
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