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ESBL-plasmids carrying toxin-antitoxin systems can be “cured” of wild-type Escherichia coli using a heat technique

BACKGROUND: Plasmid-encoded extended-spectrum beta-lactamase (ESBL)-enzymes are frequently produced by Escherichia coli. Several ESBL-plasmids contain genes for toxin-antitoxin (TA) systems, which assure the maintenance of plasmids in bacteria and prevent the cells from “post-segregational killing”....

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Detalhes bibliográficos
Main Authors: Schaufler, Katharina, Wieler, Lothar H, Semmler, Torsten, Ewers, Christa, Guenther, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177129/
https://ncbi.nlm.nih.gov/pubmed/24245987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-4749-5-34
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