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Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3

Expression of the Growth Hormone (GH)-stimulated gene Socs2 (Suppressor of Cytokine Signaling 2) is mediated by the transcription activator STAT5 (Signal Transducer and Activator of Transcription 5) and the transcription repressor BCL6 (B-Cell Lymphoma 6). ChIP-Sequencing identified Cish (Cytokine-I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Grace, LaPensee, Christopher R., Qin, Zhaohui S., Schwartz, Jessica
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176921/
https://ncbi.nlm.nih.gov/pubmed/25088465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2014.07.020
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