Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.

GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase (EC 2.4.1.69) is a key enzyme in the biosynthesis of fucosylated type 1 and 2 lactoseries structures, such as Lewis b and the H type 2 and Lewis Y, respectively, that are accumulated in colon adenocarcinoma. Analysis of the mRNA transcript...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Sun, J, Thurin, J, Cooper, H S, Wang, P, Mackiewicz, M, Steplewski, Z, Blaszczyk-Thurin, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539926/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5724
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