Strategies to Design and Analyze Targeted Sequencing Data: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

BACKGROUND: Genome-wide association studies (GWAS) have identified thousands of genetic variants that influence a variety of diseases and health-related quantitative traits. However, the causal variants underlying the majority of genetic associations remain unknown. The Cohorts for Heart and Aging R...

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Detalhes bibliográficos
Main Authors: Lin, Honghuang, Wang, Min, Brody, Jennifer A., Bis, Joshua C., Dupuis, Josée, Lumley, Thomas, McKnight, Barbara, Rice, Kenneth M., Sitlani, Colleen M., Reid, Jeffrey G., Bressler, Jan, Liu, Xiaoming, Davis, Brian C., Johnson, Andrew D., O'Donnell, Christopher J., Kovar, Christie L., Dinh, Huyen, Wu, Yuanqing, Newsham, Irene, Chen, Han, Broka, Andi, DeStefano, Anita L., Gupta, Mayetri, Lunetta, Kathryn L., Liu, Ching-Ti, White, Charles C., Xing, Chuanhua, Zhou, Yanhua, Benjamin, Emelia J., Schnabel, Renate B., Heckbert, Susan R., Psaty, Bruce M., Muzny, Donna M., Cupples, L. Adrienne, Morrison, Alanna C., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176824/
https://ncbi.nlm.nih.gov/pubmed/24951659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000350
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