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Amantadine alleviates postoperative cognitive dysfunction possibly by increasing glial cell line-derived neurotrophic factor in rats

BACKGROUND: Postoperative cognitive dysfunction is a clinical entity that is associated with poor outcome. We determined the effectiveness of amantadine in reducing surgery-induced cognitive impairment and the role of glial cell line-derived neurotrophic factor (GDNF) in this effect. METHODS: Four-m...

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Detalhes bibliográficos
Main Authors: Zhang, Junfeng, Tan, Hongying, Jiang, Wei, Zuo, Zhiyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176814/
https://ncbi.nlm.nih.gov/pubmed/25251457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000352
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