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High-dose vitamin D(3) during intensive phase treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

BACKGROUND: Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of adjunctive vitamin D on sputum culture conversion are lacking. METHODS: We conducted a multi-centre randomised c...

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Detalhes bibliográficos
Main Authors: Martineau, Adrian R., Timms, Peter M., Bothamley, Graham H., Hanifa, Yasmeen, Islam, Kamrul, Claxton, Alleyna P., Packe, Geoffrey E., Moore-Gillon, John C., Darmalingam, Mathina, Davidson, Robert N, Milburn, Heather J., Baker, Lucy V., Barker, Richard D., Woodward, Nicholas J, Venton, Timothy R., Barnes, Korina E., Mullett, Christopher J., Coussens, Anna K., Rutterford, Clare M., Mein, Charles A., Davies, Geraint R., Wilkinson, Robert J., Nikolayevskyy, Vladyslav, Drobniewski, Francis A., Eldridge, Sandra M., Griffiths, Christopher J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176755/
https://ncbi.nlm.nih.gov/pubmed/21215445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(10)61889-2
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