Hypercaloric enteral nutrition in Amyotrophic Lateral Sclerosis: a randomized double-blind placebo-controlled trial

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a rapidly fatal neurodegenerative disease with few therapeutic options. Mild obesity is associated with greater survival in ALS patients and calorie-dense diets increase survival in an ALS mouse model. We therefore hypothesized that hypercaloric die...

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Main Authors: Wills, Anne-Marie, Hubbard, Jane, Macklin, Eric A., Glass, Jonathan, Tandan, Rup, Simpson, Ericka P, Brooks, Benjamin, Gelinas, Deborah, Mitsumoto, Hiroshi, Mozaffar, Tahseen, Hanes, Gregory P., Ladha, Shafeeq S., Heiman-Patterson, Terry, Katz, Jonathan, Lou, Jau-Shin, Mahoney, Katy, Grasso, Daniela, Lawson, Robert, Yu, Hong, Cudkowicz, Merit
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176708/
https://ncbi.nlm.nih.gov/pubmed/24582471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(14)60222-1
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