Deletion of Aryl Hydrocarbon Receptor AHR in Mice Leads to Subretinal Accumulation of Microglia and RPE Atrophy

PURPOSE. The aryl hydrocarbon receptor (AHR) is a ligand-activated nuclear receptor that regulates cellular response to environmental signals, including UV and blue wavelength light. This study was undertaken to elucidate AHR function in retinal homeostasis. METHODS. RNA-seq data sets were examined...

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Main Authors: Kim, Soo-Young, Yang, Hyun-Jin, Chang, Yi-Sheng, Kim, Jung-Woong, Brooks, Matthew, Chew, Emily Y., Wong, Wai T., Fariss, Robert N., Rachel, Rivka A., Cogliati, Tiziana, Qian, Haohua, Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176417/
https://ncbi.nlm.nih.gov/pubmed/25159211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15091
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