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Development of a Fluorescence Assay for the Characterization of Brevenal Binding to Rat Brain Synaptosomes

[Image: see text] The marine dinoflagellate Karenia brevis produces a family of neurotoxins known as brevetoxins. Brevetoxins elicit their effects by binding to and activating voltage-sensitive sodium channels (VSSCs) in cell membranes. K. brevis also produces brevenal, a brevetoxin antagonist, whic...

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Detalhes bibliográficos
Main Authors: McCall, Jennifer R., Goodman, Allan J., Jacocks, Henry M., Thompson, Alysha M., Baden, Daniel G., Bourdelais, Andrea J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176390/
https://ncbi.nlm.nih.gov/pubmed/25226846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500118p
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